Medical Ailments & Application Index

Cannabis is a miraculous plant, the variety and range of the Cannabis plant is truly a miracle. the best we can find each disease requires a curtain ratio of cannabinoids, keeping in mind that nature is perfection and the entorauge effect clearly shows that some of each molecule is best together as nature intended. If one is forced to use a different strain then preferred it will still medically benefit as each strain has a bit of each molecule.
​
​Note:​
Raw Kief/Greens
Ideally one should be eating Raw Kief/Greens for the "A" molecule THCA, CBDA etc, Over and above the preferred method of medicating, each cannabinoid & Terpenes plays a roll in healing.
Medicating 
  • ​Drops/Oil Dropped under tongue for faster absorption (Soft membrane tissue).
  • Sprays, if for internal best applied through nasal sprays for soft tissue. (If Issue is eye's or ear's, apply to correlation)

~ A ~

- Aneurysms
  • Aneurysms
  • Headline 1
  • How Cannabis Aids
  • Clinical Studies
  • Methods to Medicate
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An aneurysm is a localized, blood-filled balloon-like bulge in the wall of a blood vessel.[1] Aneurysms can also be a nidus for clot formation (thrombosis) and embolization. This weakness causes the vein to bulge as blood flows through it. a blood vessel in the brain it is referred to as a cerebral aneurysm. Aneurysms are categorized as small, saccular or berry aneurysms depending on their size. particularly lethal examples include aneurysms of the Circle of Willis in the brain, aortic aneurysms affecting the thoracic aorta, and abdominal aortic aneurysms. Aneurysms can arise in the heart itself following a heart attack, including both ventricular abdominal aortic aneurysms. Aneurysms can arise in the heart itself following a heart attack, including both ventricular and atrial ​
septal ​ Most aneurysms usually go unnoticed unless they rupture or are viewed in an MRI scan. Immediately after ruptures, patients can experience double vision, severe and sudden headaches, neck stiffness and even loss of vision temporarily.
Cannabis lowers the hypothalamic set-point in the body. This causes one to begin experiencing Hypothermia, which is a very beneficial process for people who have had brain injuries. One of the causes of these injuries is an aneurysm, By inducing hypothermia, it helps prevent further damage as well as encouraging healing to the region by increasing blood flow the ECS regulates bodily functions facilitating homeostasis (relaxing the body, reducing blood pressure decreasing rupture potential). As well Cannabis/cannabinoids have properties in which dilate the arteries creating a ease of pressure in the area of the aneurysm. cannabis also has rejuvenation properties aiding in the repair of the cellular tissue making up the blood vessels. Cannabinoids are also heavily involved in embryology and cell growth and differentiation. 
The proliferation and differentiation of neural stem cells are shaped by extracellular cues provided by endocannabinoids. Adult neurogenesis is regulated by many of these same embryonic endocannabinoid mechanisms.
The proliferation and differentiation of neural stem cells are shaped by extracellular cues provided by endocannabinoids. Adult neurogenesis is regulated by many of these same embryonic endocannabinoid mechanisms. ​ potentially aiding in the cellular strengthening of the blood vessles.
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  • Vapor
  • Inhalers/Nebulizers
  • Smoking
  • Edibles/Capsules
  • Ointments/Topical
  • Tincture
  • Cannabis Oil
  • Sprays
  • Transdermal Patches
  • Raw Kief/Greens
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+ Under tongue
+ Under tongue
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-Anxiety
  • Anxiety
  • Preferred Strains
  • How Cannabis Aids
  • Patent & Lab Studies
  • Methods to Medicate
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Anxiety is an emotion characterized by an unpleasant state of inner turmoil, often accompanied by nervous behavior.
There are various types of anxiety. Existential anxiety can occur when a person faces angst, an existential crisis, or nihilistic feelings. People can also face mathematical anxiety, somatic anxiety, stage fright, or test anxiety. Social anxiety and stranger anxiety are caused when people are apprehensive around strangers or other people in general. Furthermore, anxiety has been linked with physical symptoms such as IBS and can heighten other mental health illnesses such as OCD and panic disorder.​
Cannatonic
4.3
THC 0.0/14.0%
​CBD 0.0/23.4%
CBN 0.0/0.O7%
THC/CBD Ratio 1:2
​Indica dominant
Jack Herer 
4.4
THC 18.0/23.0%
​CBD 0.03/0.2%
CBN 0.0/0.03%
THC/CBD Ratio
​Sativa Dominant
Granddaddy Purple 
4.4
THC 17.0/23.0%
CBD 0.1/0.2%
CBN 0.01/0.05%
​THC/CBD Ratio
​Indica Dominant
ACDC
4.5
THC 0.42/1.20%
CBD 16.0/24.0%
CBN 0.0/0.20%
​THC/CBD Ratio 1:20
Strawberry Cough
4.3
THC 17.0/22.0%
CBD 21.0/26.0%
CBN 0.5/1.0%
THC/CBD Ratio
​80/20% Sativa Dominant
The central amygdala (CeA) is a key structure at the limbic-motor interface regulating stress responses and emotional learning. Endocannabinoid (eCB) signaling is heavily implicated in the regulation of stress-response physiology and emotional learning processes; however, the role of eCBs in the modulation of synaptic efficacy in the CeA is still a on going learning process. Here we describe the subcellular localization of CB1 cannabinoid receptors and eCB synthetic machinery at glutamatergic synapses in the CeA and find that CeA neurons exhibit multiple mechanistically and temporally distinct modes of postsynaptic eCB mobilization. These data identify a prominent role for eCBs in the modulation of excitatory drive to CeA neurons and provide insight into the mechanisms by which eCB signaling and exogenous cannabinoids could regulate stress responses and emotional learning.
  CBD is postulated to act as an agonist to the 5HT1areceptor. Activation of the 5HT1a receptor is understood to modulate the release of serotonin in the brain. This hypothesis was confirmed in a study in which mice were pretreated with a 5HT1a antagonist, the antidepressant effects of CBD were absent. Further evidence of the role of 5HT1a is given by the observed similarities of CBD and isapirone (a 5HT1a partial agonist) in public speaking model.
Anandamide,         The Bliss Molecule: The molecule in chocolate that give the blissful feeling, Also Naturally produced in the body It is a important neurotransmitter responsible for producing joy & Happiness. (activating in many cases, including; during meditation). Anandamide is received by both CB1 & 2  cannabiniod receptors, consisting of: Hydrogen, nitrogen, Oxygen,& Carbon.) Cannabis can supplement & Balance a deficient body.
PhytoCannabiniods:     are in some ways a simplified molecular version producing the same affects and more, keying into the same receptors. Cannabiniods consist of: Hydrogen, Oxygen, & Carbon. (The 3 elements of life ( 1 Less then Anandamide, Nitrogen.)) Activating a blissful feeling and heal the body at the same time.
  • Vapor
  • Inhalers/Nebulizers
  • Smoking
  • Edibles/Capsules
  • Ointments/Topical
  • Tincture
  • Cannabis Oil
  • Sprays
  • Transdermal Patches
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​+ If taken regularly (Slower Absorption Rate)

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-Appetite 
  • Appetite
  • Preferred Strains
  • How Cannabis Aids
  • Patents & Lab Studies
  • Methods to Medicate
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Appetite is the desire to eat food, sometimes due to hunger. Appealing foods can stimulate appetite even when hunger is absent. Appetite exists in all higher life-forms, and serves to regulate adequate energy intake to maintain metabolic needs. It is regulated by a close interplay between the digestive tract, adipose tissue and the brain.
THC 4.0/7.0%
CBD 8.0/16.0%
CBN0.0/0.02%
​THC/CBD Ratio 2:5
​75/25% Sativa Dominant
THC 21.5/25.0%
​CBD 0.01/0.32%
CBN 0.01/0.05%
​THC/CBD Ratio
​90/10% Indica Dominant
THC 14.36/19.38%
​CBD  ​1.05/1.77%
​CBN 0.51/2.66%
THC/CBD Ratio
​60/50% Sativa Dominant
THC 17.0/20.0%
​CBD 0.10/13.21%
CBN 0.30/0.70%
90/10% Indica Dominant
Evidence for the role of the endocannabinoid system in food-seeking behavior comes from a variety of cannabinoid studies. Emerging data suggests that THC acts via CB1 receptors in the hypothalamic nuclei to directly increase appetite. It is thought that hypothalamic neurons tonically produce endocannabinoids that work to tightly regulate hunger. The amount of endocannabinoids produced is inversely correlated with the amount of leptin in the blood. For example, mice without leptin not only become massively obese but express abnormally high levels of hypothalamic endocannabinoids as a compensatory mechanism. Similarly, when these mice were treated with an endocannabinoid inverse agonists, such as rimonabant, food intake was reduced.  When the CB1 receptor is knocked out in mice, these animals tend to be leaner and less hungry than wild-type mice. A related study examined the effect of THC on the hedonic (pleasure) value of food and found enhanced dopamine release in the nucleus accumbens and increased pleasure-related behavior after administration of a sucrose solution. A related study found that endocannabinoids affect taste perception in taste cells In taste cells, endocannabinoids were shown to selectively enhance the strength of neural signaling for sweet tastes, whereas leptin decreased the strength of this same response. While there is need for more research, these results suggest that cannabinoid activity in the hypothalamus and nucleus accumbens is related to appetitive, food-seeking behavior.
  • Vapor
  • Inhalers/Nebulizers
  • Smoking
  • Edibles/Capsules
  • Ointments/Topical
  • Tincture
  • Cannabis Oil
  • Sprays
  • Transdermal Patches
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- Arthritis
  • Arthritis
  • Preferred Strains
  • How Cannabis Aids
  • Patents & Lab Studies
  • Methods to Medicate
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Arthritis is a term often used to mean any disorder that affects joints. Symptoms generally include joint pain and stiffness. Other symptoms may include redness, warmth, swelling, and decreased range of motion of the affected joints. In some types other organs are also affected. Onset can be gradual or sudden.  There are over 100 types of arthritis. The most common forms are osteoarthritis (degenerative joint disease) and rheumatoid arthritis. Osteoarthritis usually occurs with age and affects the fingers, knees, and hips. Rheumatoid arthritis is an autoimmune disorder that often affects the hands and feet. Other types include gout, lupus, fibromyalgia, and septic arthritis. They are all types of rheumatic disease.
4.3
THC 0.0/14.0%
​CBD 0.0/23.4%
CBN 0.0/0.O7%
THC/CBD Ratio 1:2
​Indica dominant
4.3
THC 4.0/7.0%
CBD 8.0/16.0%
CBN0.0/0.02%
​THC/CBD Ratio 2:5
​75/25% Sativa Dominant
4.5
THC 8.0/16.0%
CBD 8.0/16.0%
CBN 0.10/0.13%
THC/CBD Ratio 1:1
​70/30% Indica Dominant
4.5
THC 0.42/1.20%
CBD 16.0/24.0%
CBN 0.0/0.20%
​THC/CBD Ratio 1:20
There are two types of cannabinoid receptors, CB1 and CB2, and they are found in the body in locations such as the brain, all major organs ie, heart, liver, intestines, the immune system, nervous, lymbch, hormone, etc.
When a cannabinoid receptor is stimulated by an endocannabinoid, various physiological functions in multiple systems of the body are activated including memory, pain sensation, mood, and most pertinent to this article, appetite.  ECS activity in the central nervous system regulates food intake. This is because whenever you’re hungry your ECS sends signals to your hypothalamus (a structure in your brain that helps to regulate appetite) which lets your limbic system (an area that controls emotion) know that it’s about to “go down” with that tub of Ben & Jerry’s ice cream in the freezer.
Endocannabinoids work to slow down the process of gastrointestinal emptying and transit, and appear to stimulate the secretion of ghrelin, a hormone that increases appetite and food intake. After eating, your brain is sent satiety signals (by way of the hormone leptin) from your small intestine, which reduces activity in your ECS and lets your body know you’ve had enough to eat.
  • Vapor
  • Inhalers/Nebulizers
  • Smoking
  • Edibles/Capsules
  • Ointments/Topical
  • Tincture
  • Cannabis Oil
  • Sprays
  • Transdermal Patches
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- Autism
  • Autism
  • Headline 1
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~ C ~

- Cancer
  • Cancer
  • Strain's that Aid
  • How Cannabis Aids
  • Patents & Lab Studies
  • Method to Medicate
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 Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.  These contrast with benign tumors, which do not spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they may have other causes.Over 100 types of cancers affect humans.  of cancer in males are lung cancer, prostate cancer, colorectal cancer and stomach cancer. In females, the most common types are breast cancer, colorectal cancer, lung cancer and cervical cancer. If skin cancer other than melanoma were included in total new cancers each year, it would account for around 40% of cases. In Children ​
 acute lymphoblastic leukemia and brain tumors are most common  The risk of cancer increases significantly with age and many cancers occur more commonly in developed countries.  Rates are increasing as more people live to an old age and as lifestyle changes occur in the developing world. Cancers are a large family of diseases that involve abnormal cell growth with the potential to invade or spread to other parts of the body. They form a subset of neoplasms.
  A neoplasm or tumor is a group of cells that have undergone unregulated growth and will often form a mass or lump, but may be distributed diffusely.
All tumor cells show the six hallmarks of cancer. These characteristics are required to produce a malignant tumor. They include:​
The progression from normal cells to cells that can form a detectable mass to outright cancer involves multiple steps known as malignant progression.
4.3
THC 17.0/22.0%
CBD 0.07/0.10%
CBN 0.0/0.04%
​100% Indica Dominant
4.4
THC 14.36/19.38%
​CBD  ​1.05/1.77%
​CBN 0.51/2.66%
THC/CBD Ratio
​60/50% Sativa Dominant
4.5
THC 21.5/25.0%
​CBD 0.01/0.32%
CBN 0.01/0.05%
​THC/CBD Ratio
​90/10% Indica Dominant
4.7
THC 21.5/25.0%
​CBD 0.01/0.32%
CBN 0.01/0.05%
​THC/CBD Ratio
​90/10% Indica Dominant
4.7
THC 15.0/20.0%
CBD 0.10/0.30%
​CBN -/-%
​100% Indica Dominat
4.4
THC 17.0/20.0%
​CBD 0.10/13.21%
CBN 0.30/0.70%
90/10% Indica Dominant
4.3
THC 19.0/25.0%
CBD 0.08/0.10%
CBN 0.01/0.04%
​100% Indica Dominant
Cannabis contains at least 85 different types of cannabinoids, the active chemicals that create drug-like effects throughout the body. The impact of these cannabinoids in treating cancer symptoms as well as the side effects of cancer therapies is so favorable, cannabinoids are synthesized for legal, prescription use. Dronabinol and Nabilone/Cesamet, two synthetic pill forms of THC, are FDA-approved and currently being used to treat nausea and vomiting associated with chemo.
Cannabinoids that are known to benefit people living with cancer include CBC, CBD, CBDa, CBG, THC, and THCa. Cannabidiol (CBD) is known to relieve pain, lower inflammation, and decrease anxiety without the “high” of THC, the primary psychoactive ingredient in cannabis. In Canada, a cannabis extract containing THC and CBD called Nabiximols/Sativex is approved for pain relief in patients with advanced cancer and multiple sclerosis. According to the U.S. government’s National Cancer Institute, other effects of cannabinoids include anti-inflammatory activity, blocking cell growth, preventing the growth of blood vessels that supply tumors, fighting viruses, and relieving muscle spasms.
National Cancer Institute 
Chemical components of Cannabis, called cannabinoids, activate specific receptors throughout the body to produce pharmacologic effects, particularly in the central nervous system and the immune system.
Cannabinoids may have benefits in the treatment of cancer-related side effects.​
Note: whether the cancer is skin or internal should guide whether to utilize a topical or internal method of administering.
  • Vapor
  • Inhalers/Nebulizers
  • Smoking
  • Edibles/Capsules
  • Ointments/Topical
  • Tincture
  • Cannabis Oil
  • Sprays
  • Transdermal Patches
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~ D ~

- Diabetes 
  • Diabetes
  • Preferred Strains
  • How Cannabis Aids
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Note: Autoimmune Disorder, is responsible for over 100 diseases, including rheumatoid arthritis, Studies show people with Autoimmune, have a increase of Cannabiniod receptors in curtain areas, suggesting the body is in need of more Cannabiniods. Research has discovered that endocannabinoids are immunomodulators. Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic disorders in which there are high blood sugar levels over a prolonged period.[7]
Symptoms of high blood sugar include frequent urination, increased thirst, and increased hunger.[2] ​ 
  • Type 1 DM results from the pancreas's failure to produce enough insulin.[2] This form was previously referred to as "insulin-dependent diabetes mellitus" (IDDM) or "juvenile diabetes".[2] The cause is unknown.[2 (In all likely hood, the unnatural food we eat.)
  • ​Type 2 DM begins with insulin resistance, a condition in which cells fail to respond to insulin properly.[2] As the disease progresses a lack of insulin may also develop.[9] This form was previously referred to as "non insulin-dependent diabetes mellitus" (NIDDM) or "adult-onset diabetes".[2] The most common cause is excessive body weight (From Unnatural food) & insufficient exercise.[2]
  • Gestational diabetes is the third main form, and occurs when pregnant women without a previous history of diabetes develop high blood sugar levels.[2]
- Depression
  • Depression
  • preferred strains
  • How Cannabis Aids
  • Patents & Lab Studies
  • Methods to Medicate
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Depression is a state of low mood and aversion to activity that can affect a person's thoughts, behavior, feelings, and sense of well-being. A depressed mood is a normal temporary reaction to life events such as loss of a loved one. It is also a symptom of some physical diseases and a side effect of some drugs and medical treatments. Depressed mood is also a symptom of some mood disorders such as major depressive disorder or dysthymia.  People with a depressed mood may be notably sad, anxious, empty; or angry 
4.4
THC 14.36/19.38%
​CBD  ​1.05/1.77%
​CBN 0.51/2.66%
THC/CBD Ratio
​60/40% Sativa Dominant
4.4
THC 17.0/20.0%
​CBD 0.10/13.21%
CBN 0.30/0.70%
90/10% Indica Dominant
4.3
THC 16.00/20.00%
​CBD 0.10/0.30%
​CBN 0.0/0.30%
THC/CBD RATIO
​55/45% Sativa Dominant
4.5
THC 21.5/25.0%
​CBD 0.01/0.32%
CBN 0.01/0.05%
​THC/CBD Ratio
​90/10% Indica Dominant
The inhibitory effects of cannabinoid receptor stimulation on neurotransmitter release have caused this system to be connected to various forms of depressant plasticity. A recent study conducted with the bed nucleus of the stria terminalis found that the endurance of the depressant effects was mediated by two different signaling pathways based on the type of receptor activated. 2-AG was found to act on presynaptic CB1 receptors to mediate retrograde short-term depression (STD) following activation of L-type calcium currents, while anandamide was synthesized after mGluR5 activation and triggered autocrine signalling onto postsynapic TRPV1 receptors that induced long-term depression (LTD). Similar post-synaptic receptor dependencies were found in the striatum, but here both effects relied on presynaptic CB1 receptors. These findings provide the brain a direct mechanism to selectively inhibit neuronal excitability over variable time scales. By selectively internalizing different receptors, the brain may limit the production of specific endocannabinoids to favor a time scale in accordance with its needs.
CBD is postulated to act as an agonist to the 5HT1areceptor. Activation of the 5HT1a receptor is understood to modulate the release of serotonin in the brain. This hypothesis was confirmed in a study in which mice were pretreated with a 5HT1a antagonist, the antidepressant effects of CBD were absent. Further evidence of the role of 5HT1a is given by the observed similarities of CBD and isapirone (a 5HT1a partial agonist) in public speaking model.
Anandamide,         The Bliss Molecule: is the bodies version of a Phyto-cannabiniod The molecule in chocolate that give the blissful feeling, Also Naturally produced in the body, it is a important neurotransmitter responsible for the production of joy & happiness. (activating in many cases, including; during meditation). Anandamide is received by both CB1 & 2  cannabiniod receptors, consisting of: Hydrogen, nitrogen, Oxygen,& Carbon.) Cannabis can suupliment & Balance a deficient body.
PhytoCannabiniods:     are in some ways a simplified molecular version producing the same affects and more, keying into the same receptors. Cannabiniods consist of: Hydrogen, Oxygen, & Carbon. (The 3 elements of life ( 1 Less then Anandamide, Nitrogen.)) Activating a blissful feeling and heal the body at the same time.
  • Vapor
  • Inhalers/Nebulizers
  • Smoking
  • Edibles/Capsules
  • Ointments/Topical
  • Tincture
  • Cannabis Oil
  • Sprays
  • Transdermal Patches
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~ E ~

~ I ~

Inflammation
  • Inflammation
  • Preferred Strains
  • How Cannabis Aids
  • Patents & Lab Studies
  • Methods to Medicate
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Inflammation (from Latin inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators. The function of inflammation is to eliminate the initial cause of cell injury, clear out necrotic cells and tissues damaged from the original insult and the inflammatory process, and initiate tissue repair.  
Ingrid
4.3
THC 21.0/25.0%
​CBD O.0/0.6%
CBN 0.O/O.3%
​75/25% Indica Dominant
ACDC
4.5
THC 0.42/1.20%
CBD 16.0/24.0%
CBN 0.0/0.20%
​THC/CBD Ratio 1:20
Critical Mass
4.3
THC 15.0/23.0%
​CBD 0.01/0.07%
CBN -/-%
​80/20 Indica Dominant
Harlequin
4.3
THC 4.0/7.0%
CBD 8.0/16.0%
CBN0.0/0.02%
​THC/CBD Ratio 2:5
​75/25% Sativa Dominant
The CB2 receptor in the tissue plays a crucial role in inhibiting inflammation. If the receptor is activated, the cell releases fewer pro-inflammatory signal substances, or cytokines. The scientists have now discovered that the substance beta-carophyllene, which composes between 12 and 35 percent of the cannabis plant’s essential oil, activates the CB2 receptor selectively.
Clinical Studies
2004 - Study ~ The endogenous cannabinoid system protects against colonic inflammation.
2006 - Study ~ Endocannabinoid overactivity and intestinal inflammation.
2010 - Study ~ The endocannabinoid system in the inflammatory and neurodegenerative processes of multiple sclerosis and of amyotrophic lateral sclerosis.
2007 - Study ~ The endocannabinoid system in targeting inflammatory neurodegenerative diseases.
2007 - News ~ Endocannabinoids appear to play important role in regulating inflammation.
Patents
US6410588  Apr 14, 1999Jun 25, 2002The Mathilda And Terence Kennedy Institute Of RheumatologyUse of                                       cannabinoids as anti-inflammatory agents
US9763894    Dec 5, 2007Sep 19, 2017Virginia Commonwealth University Inflammation therapy
​For More Clinical Studies Check Out, ​For More Patents Check Out,
Note: Depending on the type of inflammation, will dictate the method to medicate. whether topically or internal.
  • Vapor
  • Inhalers/Nebulizers
  • Smoking
  • Edibles/Capsules
  • Ointments/Topical
  • Tincture
  • Cannabis Oil
  • Sprays
  • Transdermal Patches
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  • + ?
  • ​+ ?
- Insomnia
  • Insomnia
  • Preferred Strains
  • How Cannabis Aids
  • Patents & Lab Studies
  • Methods to Medicate
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Insomnia, also known as sleeplessness, is a sleep disorder where people have trouble sleeping. They may have difficulty falling asleep, or staying asleep as long as desired. Insomnia is typically followed by daytime sleepiness, low energy, irritability, and a depressed mood. Insomnia can occur independently or as a result of another problem. Conditions that can result in insomnia include psychological stress, chronic pain, heart failure, hyperthyroidism, heartburn, restless leg syndrome, menopause, certain medications, and drugs such as caffeine, nicotine, and alcohol. 
Granddaddy Purple
4.3
THC 18.0/23.0%
CBD 0.10/0.20%
CBN 0.01/0.05%
​Indica Dominant 
Tahoe OG KUSH
4.3
THC 20.0/25.0%
CBD 0.07/0.20%
CBN 0.01/0.05%
​60/40%<> 50/50% ? Dominant
Blackberry Kush 
4.4
THC 16.00/21.00%
​CBD  ​-/-%
​CBN 0.50/2.00%
THC/CBD Ratio
​Indica Dominant
Northern Lights
4.3
THC 17.0/20.0%
​CBD 0.10/13.21%
​CBN 0.30/0.70%
​90/10% Sativa Dominant
The endocannabinoid system has broad influence over areas of the brain involved in sensations such as pain perception, movement, emotion, cognition, and sleep. Early research suggests that CBD consumption has the potential to improve sleep. The effect of CBD on alertness is biphasic. At low doses it has been shown to increase alertness, though at higher doses, patients report a very calming effect.  The two major cannabinoids found in cannabis are thought to be responsible for cannabis’ effectiveness at muscle pain, tension & Spasm relief. There’s strong evidence that suggests that cannabinoid-induced reductions in muscle tension, tremors and spasticity are due to interaction with the cannabinoid receptors, CB1 and CB2, of the endocannabinoid system. By interacting with the CB1 and CB2 receptors, cannabinoids help regulate the excitatory and inhibitory neurotransmitters necessary to curtail spasms, and ease tension. this effect takes place throughout the body, as the endocannabiniod system regulates all major  organs and all function systems eg, immune, nervous system, etc. This effect is greater with the Indica strains ( as the Sativa strains are more of a cognitive stimulant ). 
Note, Each person reaction rate varies, but the average person has the best results medicating approximately 30 minutes to 1 hour before one lays down to sleep.
  • Vapor
  • Inhalers/Nebulizers
  • Smoking
  • Edibles/Capsules
  • Ointments/Topical
  • Tincture
  • Cannabis Oil
  • Sprays
  • Transdermal Patches
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~ L ~

- Liver Disease's
  • Liver Disease's
  • Preferred Strains 
  •  How Cannabis Aids
  • Patents & Lab Studies
  • Methods to Medicate
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Common Liver Disease's;  Hepatitis, Cirrhosis, & Haemochromatosis
Liver disease is a general term for conditions which affect the liver. They can manifest themselves in forms of various symptoms associated with metabolism, blood sugar, immune system and fat absorption problems. Many liver diseases are caused by increased levels of bilirubin in the system. It comes from the breakup of the hemoglobin of dead red blood cells. Normally it is washed from the blood and excreted through bile. Most common liver diseases are hepatitis (liver inflammation caused by various viruses), cirrhosis (formation of fibrous tissues in the liver caused by alcoholism, viral hepatitis and liver-​
toxic chemicals) and haemochromatosis (a hereditary condition which causes the accumulation of iron in the system).  At least 30 million Americans have some form of liver disease. In fact, liver disease was ranked at the twelfth most common cause of death in the United States.  ​
Cheese
THC 10/12%
CBD -/0.19
​CBN 0.05/0.08%
Critical Kush
THC 21.5/25.0%
​CBD 0.01/0.32%
CBN 0.01/0.05%
THC/CBD Ratio
​90/10% Indica Dominant
Death Budda
THC 21.5/25.0%
​CBD 0.01/0.32%
CBN 0.01/0.05%
​THC/CBD Ratio
​90/10% Indica Dominant
Mother of Berries
THC 19/22%
​CBD 0.20/1.00%
​CBN 3.00/4.00%
​THC/CBD Ratio
​90/10% Indica Dominant
Blue Dream
THC 14.36/19.38%
​CBD  ​1.05/1.77%
​CBN 0.51/2.66%
THC/CBD Ratio
​60/50% Sativa Dominant
liver disease is ultimately a inflammation of the liver whether caused by viral, substance, or blood Research shows cannabis not only alleviates pain and inflammation but also restores liver functioning.
This is huge! When the liver becomes severely damaged, it loses the ability to heal itself. .
Here’s some of what you need to know about cannabis and liver disease.  Cannabis has Inflammatory properties, Cellular, bone and tissue regeneration properties, mineral enhancing properties, mineral regeneration properties, mineral transport properties, regulates regulatory systems; immune, hormone, nervous, hunger & more.
Check out; Liver Disease
​Cannabis Patents
Cannabis Science & Nutrition.
Laboratory studies;
​2005 Hebrew University Medical School Study,                      - Showing endocannabinoids help modulate inflammatory responses along with                                                                                                                                                              vascular changes.
2011 study published in Cell Death and Disease,                    - revealed CBD (one of many cannabinoids found in cannabis) plays a crucial role in                                                                                                                                                       the treatment of liver disease.
​2011 study Published in British Journal of Pharmacology,   - “Cannabidiol restores liver function, normalizes 5-HT levels and improves brain                                                                                                                                                              pathology in accordance with normalization of brain function. Therefore, the effects                                                                                                                                                    of cannabidiol may result from a combination of its actions in the liver and brain.”
​Patents  (There are a abundance of patents, here's a few related)
​US6410588
WO1994012667A1     Nov 29, 1993, Jun 9, 1994The United States Department Of The ArmyInhibitors of arachidonic acid                                              metabolites for preventing neurological damage​
US20080139635       *Dec 5, 2007, Jun 12, 2008Virginia Common Wealth UniversityInflammation Therapy​

For more Patents Check out   Cannabis Patents
For more Scientific Studies Check out;
​> List's of Scientific Cannabis Studies
> List's of Endocannabiniod & Cannabis Studies
> List's of Delta 9-THC & Cannabis Studies
​> List's of CBD & Cannabis Studies
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+ Soft tissue under tongue

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~ N ~

- Nausea
  • Nausea
  • Strains that Aid
  • How Cannabis Aids
  • Patents & Lab Studies
  • Methods to Medicate
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Nausea is a sensation of unease and discomfort in the upper stomach with an involuntary urge to vomit. It may precede vomiting, but a person can have nausea without vomiting. When prolonged, it is a debilitating symptom.
Nausea is a non-specific symptom, which means that it has many possible causes. Some common causes of nausea are motion sickness, dizziness, migraine, fainting, low blood sugar, gastroenteritis (stomach infection) or food poisoning. Nausea is a side effect of many medications including chemotherapy, or morning sickness in early pregnancy. Nausea may also be caused by anxiety, disgust and depression.
4.5
4.4
THC 15.0/25.0%
​CBD 15.0/25.0%%
​CBN -/-%
THC/CBD Ratio 1:1
​100% Sativa Dominant
THC 15.0/22.0%
CBD 0.01/0.10%
​CBN 0.0/0.20%
​Sativa Dominant
4.4
THC 17.0/20.0%
​CBD 0.10/13.21%
CBN 0.30/0.70%
90/10% Indica Dominant
4.2
THC 16.0/19.0%
CBD 0.1/0.30%
CBN -/-%
​60/40% Indica Dominant
Nausea and vomiting can be categorized with appetite stimulation. They are part of the same mechanism that is governed by the body’s endocannabinoid system, which is supplemented by cannabinoids from inside or a outside sources, ie. marijuana.
Cannabis works by blocking the binding of serotonin and dopamine, both of which are associated with CINV, at receptor sites. Some of the body’s endocannabinoid receptors exist within emetic reflex pathways, making them a promising target for managing CINV. The dorsal vagal complex (DVC) in the brainstem is the overall regulator of emesis (nausea/vomiting), and it is responsible for communication between signals in the blood (like chemotherapy) and the nerve cells that initiate emesis. The DVC and gastrointestinal tract have endocannabinoid receptors, and all have shown to exhibit anti-emetic responses when the receptors are activated by Δ9-THC.
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  • Tincture
  • Cannabis Oil
  • Sprays
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~ O ~

- (O.C.D) Obsesive Compulsive Disorder
  • (O.C.D)
  • Preferred Strains
  • How Cannabis Aids
  • Patents & Lab Studies
  • Methods to Medicate
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Obsessive–compulsive disorder (OCD) is a mental disorder where people feel the need to check things repeatedly, perform certain routines repeatedly (called "rituals"), or have certain thoughts repeatedly. People are unable to control either the thoughts or the activities for more than a short period of time.  The cause is unknown. There appear to be some genetic components with both identical twins more often affected than both non-identical twins. Risk factors include a history of child abuse or other stress inducing event. Some cases have been documented to occur following infections. The diagnosis is based on the symptoms and requires ruling out other drug related or medical causes. Rating scales such as the Yale–Brown Obsessive Compulsive Scale (Y-BOCS) can be used to assess the severity. Other disorders with similar symptoms include anxiety disorder, major depressive disorder, eating disorders, tic disorders, and obsessive–compulsive personality disorder.
4.4
THC 17.0/20.0%
​CBD 0.10/13.21%
CBN 0.30/0.70%
90/10% Indica Dominant
4.5
THC 0.42/1.20%
CBD 16.0/24.0%
CBN 0.0/0.20%
​THC/CBD Ratio 1:20
4.3
THC 15.0/18.0%
​CBD 0.01/0.13%
​CBN 0.01/0.05%
​60/40% Sativa Dominant
4.4
THC 14.36/19.38%
CBD 1.05/1.77%
CBN 0.51/2.66%
​60/40% Sativa Dominant 
Cannabidiol (CBD), one of the main components of Cannabis sp., presents clinical and preclinical anxiolytic properties. Recent results using the marble-burying test (MBT) suggest that CBD can also induce anticompulsive-like effects. Meta-chloro-phenyl-piperazine (mCPP) is a nonspecific serotonergic agonist (acting mainly at 5HT1A, 5HT2C and 5HT1D receptors) reported to increase symptoms in OCD patients and block the anticompulsive-like effect of serotonin reuptake inhibitors (SRIs) in animal models. The aim of this study was to investigate the interference of CBD on mCPP effects in repetitive burying. Administration of mCPP showed dual effects in the MBT, increasing the number of buried marbles at lower (0.1 mg/kg) while decreasing it at higher doses (1 mg/kg), an effect not related to a general increase in anxiety-like behavior. As found previously, CBD (30 mg/kg) and the positive control fluoxetine (FLX; 10 mg/kg) decreased burying behavior without changing general exploratory activity. A similar effect was found when subeffective doses of CBD (15 mg/kg) and FLX (3 mg/kg) were administered together. These subeffective doses alone were also able to block mCPP-induced repetitive burying. The results, in addition to reinforcing a possible anticompulsive effect of CBD, also suggest that mCPP-induced repetitive burying could be a useful test for the screening of compounds with presumed anticompulsive properties.
Studies
- Study Published, 25 october 2013,  Cannabibiol reverses the mCPP-induced increase in marble-burying behavior.
​- Study, 1 December 2010, Behavioural Brain Research.    Intra-dorsal periaqueductal gray administration of                                                                                           cannabidiol blocks panic-like response by activating 5-HT1A receptors.
- 2003 - Study ~ Effects of THC on Behavioral Measures of Impulsivity in Humans.
Patent
US9040580    *May 18, 2011May 26, 2015Braintropia Co., Ltd. Method for prevention or treatment of degenerative                                            neurological brain disorders
​For more Studies check out,
- List of Scientific Cannabis Studies
​- List of Endocannabiniods & Cannabis Studies
​- List of THC & Cannabis Studies
​- List of CBD & Cannabis Studies
​For more Patents check out,
​- Cannabis Patents
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~ P ~

- Pain
  • Pain
  • Preferred strains
  • How Cannabis Aids
  • Patents & Lab Studies
  • Method to Medicate
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Pain is a distressing feeling often caused by intense or damaging stimuli. Because it is a complex, subjective phenomenon, defining pain has been a challenge. The International Association for the Study of Pain's widely used definition states: "Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage." In medical diagnosis, pain is regarded as a symptom of an underlying condition.
Harlequin
ACDC
4.5
THC 0.42/1.20%
CBD 16.0/24.0%
CBN 0.0/0.20%
​THC/CBD Ratio 1:20
4.3
THC 4.0/7.0%
CBD 8.0/16.0%
CBN0.0/0.02%
​THC/CBD Ratio 2:5
​75/25% Sativa Dominant
Blackberrry Kush
4.3
THC 16.0/21.0%
CBD -/-% 
CBN 0.50/2.0%
​Indica Dominant
Cannabinoids have shown significant promise in basic experiments on pain. Peripheral nerves that detect pain sensations contain abundant receptors for cannabinoids, and cannabinoids appear to block peripheral nerve pain in experimental animals. Even more encouraging, basic studies suggest that opiates and cannabinoids suppress pain through different mechanisms. If that is the case, marijuana-based medicines could perhaps be combined with opiates to boost their pain-relieving power while limiting their side effects.
 Note: Depending on the location of the pain, will determine the method of administering. ie. surface/topical pain apply oil ointment topically, if more internal smoke, edibles etc.  ?
  • Vapor
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  • Cannabis Oil
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- (PTSD) Post Traumatic Stress Syndrome
  • PTSD
  • Preferred Strains
  • How Cannabis Aids
  • Patents & Lab Studies
  • Methods to Medicate
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a mental disorder that can develop after a person is exposed to a traumatic event, such as sexual assault, warfare, traffic collisions, or other threats on a person's life. Symptoms may include disturbing thoughts, feelings, or dreams related to the events, mental or physical distress to trauma-related cues,  and an increase in the fight-or-flight response. A person with PTSD is at a higher risk for suicide and intentional self-harm.  The main treatments for people with PTSD are counselling and medication. A number of different types of therapy may be useful. This may occur one-on-one or in a group. Antidepressants of the selective serotonin reuptake inhibitor type are the first-line medications for PTSD and result in benefit in about half of people. It was officially recognized by the American Psychiatric Association in 1980 in the third edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-III).
4.4
THC 14.36/19.38%
CBD 1.05/1.77%
​CBN 0.51/2.66%
​60/40% Sativa Dominant
4.2
THC 10.0/19.0%
​CBD 0.01/0.10%
​CBN O.O/O.03%
75/25% Sativa Dominant
4.5
THC 12.0/23.0%
CBD 0.0/0.06%
CBN 0.0/0.10%
​70/30% Sativa Dominant
4.3
THC 13.0/21.0%
​CBD 0.0/0.10%
CBN 0.0/0.05%
​70/30% Sativa Dominant
 Patients who suffered from PTSD had over a 50% reduction in their anandamide levels
Anandamide is an important neurotransmitter, that’s also considered to be the “body’s own THC.” In fact, as it’s a source of joy and happiness, it’s often called the body’s “bliss molecule.” Cannabis can help correct this clinical deficiency. Interestingly, other activities including exercise or eating dark chocolate, stimulate production of anandamide. You’ve heard of the “runner’s high?” Accumulating evidence suggests anandamide is responsible for creating this “natural high.”
Another way cannabis helps with PTSD is through a mechanism called “aversive memory extinction.” PTSD patients frequently complain of recurrent memories of traumatic events. THC actually helps patients “forget” these memories to a point where they are far less painful. 
​ CBD is postulated to act as an agonist to the 5HT1areceptor. Activation of the 5HT1a receptor is understood to modulate the release of serotonin in the brain. This hypothesis was confirmed in a study in which mice were pretreated with a 5HT1a antagonist, the antidepressant effects of CBD were absent. Further evidence of the role of 5HT1a is given by the observed similarities of CBD and isapirone (a 5HT1a partial agonist) in public speaking model.
Clinical Studies
2005 - Study ~ Enhancing Cannabinoid Neurotransmission Augments the Extinction of Conditioned Fear.
2010 - Study ~  Motion Sickness, Stress and the Endocannabinoid System.
2010 - Study ~ Deficiency in Endocannabinoid Signaling in the Nucleus Accumbens Induced by Chronic Unpredictable Stress.
2009 - Editorial ~ The Endocannabinoid System in the Brain: From Biology to Therapy.
Patents
​US5462946  Mar 20, 1992Oct 31, 1995The United States Of America As Represented By The Department Of Health                        And Human Services Nitroxides as protectors against oxidative stress
​
For More Clinical Studies Check out,​For more Patents check out,​
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​

~ S ~

- Stress
  • Stress
  • Preferred Strains
  • How Cannabis Aids
  • Patents & Lab Studies
  • Methods to Medicate
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Physiological or biological stress is an organism's response to a stressor such as an environmental condition. Stress is the body's method of reacting to a challenge. Stimuli that alter an organism's environment are responded to by multiple systems in the body. The autonomic nervous system and hypothalamic-pituitary-adrenal (HPA) axis are two major systems that respond to stress. The sympathoadrenal medullary (SAM) axis may activate the fight-or-flight response through the sympathetic nervous system, which dedicates energy to more relevant bodily systems to acute adaption to stress. 
 The SAM and HPA axes are regulated by a wide variety of brain regions, including the limbic system, prefrontal cortex, amygdala, hypothalamus, and stria terminalis.  Through these mechanisms, stress can alter memory functions, reward, immune function, metabolism and susceptibility to diseases. Definitions of stress differ; however, one system proposed by Elliot and Eisdorfer suggests five types of stress. The five types of stress are labeled "acute time-limited stressors", "brief naturalistic stressors", "stressful event sequences", "chronic stressors", and "distant stressors". An acute time-limited stressor involves a short term challenge, while a brief naturalistic stressor involves an event that is normal but nevertheless challenging. A stressful event sequence is a stressor that occurs, and then continues to yield stress into the immediate future. A chronic stressor involves exposure to a long-term stressor, and a distant stressor is a stressor that isn't immediate.
Granddaddy Purple
THC 17.0/23.0%
CBD 0.1/0.2%
CBN 0.01/0.05%
​THC/CBD Ratio
​Indica Dominant
Jack Herer
THC 18.0/23.0%
​CBD 0.03/0.2%
CBN 0.0/0.03%
THC/CBD Ratio
​Sativa Dominant
Cnnatonic
THC 0.0/14.0%
​CBD 0.0/23.4%
CBN 0.0/0.O7%
THC/CBD Ratio 1:2
​Indica dominant
Strawberry Cough
THC 17.0/22.0%
CBD 21.0/26.0%
CBN 0.5/1.0%
THC/CBD Ratio
​80/20 Sativa Dominant
ACDC
THC 0.42/1.20%
CBD 16.0/24.0%
CBN 0.0/0.20%
​THC/CBD Ratio 1:20
THC (psychoactive)  and CBD (non-psychoactive) have been shown in many medical studies to slow the secretion of molecules that create a stressful response. In chronic stress, the metabolic switch that controls the release of glucocorticoids is set on high or is even broken in the on position.  Insomnia, tantrums, internalized anger and a host of other negative mental disorders are the unfortunate consequences.   The effectiveness of THC in reducing fear and anxiety brain activity was proven with MRI scans.
"CBD is postulated to act as an agonist to the 5HT1areceptor. Activation of the 5HT1a receptor is understood to modulate the release of serotonin in the brain. This hypothesis was confirmed in a study in which mice were pretreated with a 5HT1a antagonist, the antidepressant effects of CBD were absent. Further evidence of the role of 5HT1a is given by the observed similarities of CBD and isapirone (a 5HT1a partial agonist) in public speaking model.
Clinical Studies
2005 - Study ~ Enhancing Cannabinoid Neurotransmission Augments the Extinction of Conditioned Fear.
2010 - Study ~  Motion Sickness, Stress and the Endocannabinoid System.
2010 - Study ~ Deficiency in Endocannabinoid Signaling in the Nucleus Accumbens Induced by Chronic Unpredictable Stress.
2009 - Editorial ~ The Endocannabinoid System in the Brain: From Biology to Therapy.
Patents
​US5462946  Mar 20, 1992Oct 31, 1995The United States Of America As Represented By The Department Of Health                        And Human Services Nitroxides as protectors against oxidative stress
​
For More Clinical Studies Check out,​For more Patents check out,
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  • +
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  • +
  • ​+

~ T ~

Tourette's Syndrome
  • Tourette's Syndrome
  • Preferred Strains
  • How Cannabis Aids
  • Patents & Lab Studies
  • Method to Medicate
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>
Tourette’s syndrome is a hereditary neuropsychiatric disorder that manifests in childhood and is typified by physical and vocal tics, such as repetitive jerking movements or (often socially-unacceptable) speech. Cannabis may help with various symptoms of Tourette’s, including reducing  anxiety and frequency of tics.  It is not clear precisely what this mechanism is, but it is thought that it may lie in the densely-clustered cannabinoid receptors in the basal ganglia and hippocampus, areas of the brain that are fundamentally involved in the control of behaviour and movement, and that are known to be abnormal in affected individuals.
Super Silver Haze
THC 14.0/23.0%
​CBD 14.0/23.0%
CBN 1.0/2.0%
​Ratio 1:1
​80/20% Sativa Dominant
Blue Cheese
THC 18.0/22.0%
CBD 0.8/1.8%
CBN -/-%
​80/20% Indica Dominant 
Critical Kush
THC 21.5/25.0%
​CBD 0.01/0.32%
CBN 0.01/0.05%
​THC/CBD Ratio
​90/10% Indica Dominant
Blue Dream
THC 14.36/19.38%
​CBD  ​1.05/1.77%
​CBN 0.51/2.66%
THC/CBD Ratio
​60/50% Sativa Dominant
Durban Poison
THC 15.0/25.0%
​CBD 15.0/25.0%%
​CBN -/-%
THC/CBD Ratio 1:1
​100% Sativa Dominant
Green Dream
THC 20.0/23.0%
CBD -/-%
​CBN -/-%
THC/CBD Ratio
60/40% Indica Dominant
Mendo Breath
THC 19.0/20.0%
CBD 0.10/0.60%
​CBN 0.01/0.03%
70/30% Indica Dominant
OG Kush
THC 16.00/20.00%
​CBD 0.10/0.30%
​CBN -/-%
THC/CBD RATIO
​55/45% Sativa Dominant
Sour Diesel
THC 21.50/27.00%
CBD 0.74/1.30%
​CBN 1.56/4.31%
THC/CBD Ratio
​90/10% Sativa Dominant
Tourette's syndrome is a disorder which has not yet been conclusively identified, although observation's and studies have suggested that the nervous system and/or more likely the brain is the system in which is suspected to be the area of origin. Scans conclusively show that subjects in question have abnormal/hyperactive assault if you will on the neurotransmitters, possibly caused by inflammation of the neurotransmitters, or the result of, compounding to the problem. this inflammation, if not the result of the ailment may not only cause the ailment but neuro-inflammatory problems also  interfere with receptors such as the glutamate receptors but also cascade throughout ALL factions of the nervous system, including the peripheral nervous system through to the autonomic nervous system, causing disfunction anywhere in the body. 
​Cannabis (Cannabiniods) Not only creates homeostasis/regulation throughout  EVERY regulatory system in the body eg, brain, nervous system. immune, hormone, lymph, digestive, reproductive, etc. but as well regenerates cellular, bone, brain & muscle tissue, and Vitamin's & minerals, it's also a mineral transporter, enhancer, and on and on, Cannabis (Cannabiniods) cause more dopamine production as well, which facilitates retrograde inhibitions ( a way of modulating the speed of the neurotransmittion ). Cannabis then competes with dopamine for the dopamine binding sites on dopamine transporters. if enough cannabis/cannabinoids fill the bindings sites, the dopamine can't get in, resulting in more dopamine left for retrograde inhibition which results in a slower more controlled neurotransmittion and better ability to focus and successfully complete tasks.
Laboratory Studies
1988 American Psychological Association, Marijuana & Tourette's Syndrome. Journal of Clinical Psychopharmacology
1998 Germany @ the Clinic for Psychiatry, Socialpsychiatry and Psychotherapy, led by Medical Scientist Kirsten Muller-Vahl
2001 Journal of the International Parkinson's and movement Disorder Society
​Study Combined treatment of Tourette's Syndrome with Delta 9 THC & Dopamine receptors Antagonists  
 2003 - Study ~ Delta 9-tetrahydrocannabinol (THC) is effective in the treatment of tics in Tourette syndrome: a 6-week randomized trial.
Patent  (There is a abundance of patents, here's a few related examples)
US6630507                 A particular disclosed class of cannabinoids useful as neuroprotective antioxidants is formula (I)                                               wherein the R  group is independently selected from the group consisting of H, CH3, and COCH3.
​WO1994012667A1   Nov 29, 1993Jun 9, 1994The United States Department Of The ArmyInhibitors of arachidonic acid                                              metabolites for preventing neurological damage​
​
For More Patents Check out   Cannabis Patents and 
For More Scientific Studies Check out the List's of;
​> List's of Scientific Cannabis Studies
> List's of Endocannabiniod & Cannabis Studies
> List's of Delta 9-THC & Cannabis Studies
​> List's of CBD & Cannabis Studies


  • Vapor
  • Inhalers/Nebulizers
  • Smoking
  • Edibles/Capsules
  • Ointments/Topical
  • Tincture
  • Cannabis Oil
  • Sprays
  • Transdermal Patches
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+
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+ If taken regular (Not Fast Absorption) 

+ Soft tissue under tongue (Fast Absorption)
+ Soft tissue or Smoke

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  • Headline 1
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