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Changing Medicine Together!
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Apetite
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Preferred Strains
THC 4.0/7.0%
CBD 8.0/16.0% CBN0.0/0.02% THC/CBD Ratio 2:5 75/25% Sativa Dominant |
THC 21.5/25.0%
CBD 0.01/0.32% CBN 0.01/0.05% THC/CBD Ratio 90/10% Indica Dominant |
THC 14.36/19.38%
CBD 1.05/1.77% CBN 0.51/2.66% THC/CBD Ratio 60/50% Sativa Dominant |
THC 17.0/20.0%
CBD 0.10/13.21% CBN 0.30/0.70% 90/10% Indica Dominant |
Preferred Methods to Medicate
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General appetite Information
Appetite is the desire to eat food, sometimes due to hunger. Appealing foods can stimulate appetite even when hunger is absent. Appetite exists in all higher life-forms, and serves to regulate adequate energy intake to maintain metabolic needs. It is regulated by a close interplay between the digestive tract, adipose tissue and the brain. Loss of appetite can be from a range of different issue's, from a imbalance, mood, stress, or a ailment, Regardless of why your desire to eat is governed by our hunger receptors which is regulated by the endocannabinoid system. when Cannabis is administered it stimulates the endocannabinoid system, stimulating your hunger.
Science, How Cannabis Aids
Evidence for the role of the endocannabinoid system in food-seeking behavior comes from a variety of cannabinoid studies. Emerging data suggests that THC acts via CB1 receptors in the hypothalamic nuclei to directly increase appetite. It is thought that hypothalamic neurons tonically produce endocannabinoids that work to tightly regulate hunger. The amount of endocannabinoids produced is inversely correlated with the amount of leptin in the blood. For example, mice without leptin not only become massively obese but express abnormally high levels of hypothalamic endocannabinoids as a compensatory mechanism. Similarly, when these mice were treated with an endocannabinoid inverse agonists, such as rimonabant, food intake was reduced. When the CB1 receptor is knocked out in mice, these animals tend to be leaner and less hungry than wild-type mice. A related study examined the effect of THC on the hedonic (pleasure) value of food and found enhanced dopamine release in the nucleus accumbens and increased pleasure-related behavior after administration of a sucrose solution. A related study found that endocannabinoids affect taste perception in taste cells In taste cells, endocannabinoids were shown to selectively enhance the strength of neural signaling for sweet tastes, whereas leptin decreased the strength of this same response. While there is need for more research, these results suggest that cannabinoid activity in the hypothalamus and nucleus accumbens is related to appetitive, food-seeking behavior. Eating DisordersAs mentionrd above CB1R are also involved in eating behavior. CB1R knockout mice eat less than do wild types, and CB1R antagonists reduce the food intake in wild-type mice (Di Marzo et al., 2001). CB1R antagonists and inverse agonists also suppress operant responding for food rewards (Cooper, 2004). In a 12-week study with CB1R inverse agonist, taranabant, the animals lost weight over the entire range of tested doses (Addy et al., 2008). CB1R antagonists to aid weight loss are being developed in humans (Cota et al., 2003). The most advanced of such compounds is the inverse agonist, rimonabant, with which the reduction in body weight, waist circumference, and improved lipid and glucose metabolism in obese individuals has been observed (Vickers and Kennett, 2005). CB1R research may also help treat forms of anorexia. Restricting type AN and binging/purging type are associated with distinct alleles of the CNR1 gene (Siegfried et al., 2004).
Loss of Appetite:
Smoke less. Letting the cannabiniods get out the system a bit allows the body to in a sense become less familiar with the cannabiniod, creates the body to respond more aggressively with a hunger sensation.
Over Eating:
taking cannabis regularly will allow the ECS to reach homeostasis, regulating all other phyisiopathological systems including hunger & the digestive system.
Smoke less. Letting the cannabiniods get out the system a bit allows the body to in a sense become less familiar with the cannabiniod, creates the body to respond more aggressively with a hunger sensation.
Over Eating:
taking cannabis regularly will allow the ECS to reach homeostasis, regulating all other phyisiopathological systems including hunger & the digestive system.
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The Munchies
Cannabis promoting Appetite for all range of issue's from mental to disorders & ailments.
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Regulating Hunger
Havard, american journal of Science & 3 other studies show cannabis promotes weight loss
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Laboratory Studies
2000 - Study ~ Endogenous cannabinoids and appetite.
2003 - Study ~ Endogenous cannabinoid system as a modulator of food intake.
2003 - Study ~ The cannabinoid system: a role in both the homeostatic and hedonic control of eating?
2000 - Study ~ Endogenous cannabinoids and appetite.
2003 - Study ~ Endogenous cannabinoid system as a modulator of food intake.
2003 - Study ~ The cannabinoid system: a role in both the homeostatic and hedonic control of eating?
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