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~ Anxiety ~

Page Legend
  • Preferred Strains
  • Methods to medicate
  • Videos
  • Overview
  • Symptoms
  • Standard Medications
  • Side affects of Medications
  • How Cannabis Aids
  • Clinical Studies
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Preferred Strains 
Note: CBD RICH Strains are Typically Best for Anxiety. 
  • ​Each Person is different (Best to try in smaller doses, to find Best Match for your Body Chemistry)!
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THC 17.0/22.0%
CBD 21.0/26.0%
CBN 0.5/1.0%
THC/CBD Ratio
​80/20% Sativa Dominant

THC 0.0/14.0%
​CBD 0.0/23.4%
CBN 0.0/0.O7%
THC/CBD Ratio 1:2
​Indica dominant

THC 18.0/23.0%
​CBD 0.03/0.2%
CBN 0.0/0.03%
THC/CBD Ratio
​Sativa Dominant

THC 17.0/23.0%
CBD 0.1/0.2%
CBN 0.01/0.05%
​THC/CBD Ratio
​Indica Dominant

THC 0.42/1.20%
CBD 16.0/24.0%
CBN 0.0/0.20%
​THC/CBD Ratio 1:20

Preferred Methods to Medicate
Note: when possible eat/drink raw kief/greens over & above the method to medicate, maximize Amino Acids & Cannabiniods like THCA, CBDA, etc, missing from modulation/decarboxylation. 
  • Vapour
  • Inhalers/Nebulizers
  • Smoking
  • Edibles/Capsules
  • Ointments/Topical
  • Tincture
  • Cannabis Oil
  • Sprays
  • Transdermal Patches
  • ​Raw Kief/Greens
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Social Anxieties
Anxieties & Cannabis
​Cannabis.net
​
Anxiety
Therapeutic Cannabis 
​Microdosing
Allen I. Fankel, MD
Anxiety & Insomnia: Using Cannabis for Treatment
GreenBridgeMedical.com


Anxiety, Overview
Anxiety is an emotion characterized by an unpleasant state of inner turmoil, often accompanied by nervous behavior, such as pacing back and forth, somatic complaints, and rumination.  It is the subjectively unpleasant feelings of dread over anticipated events, such as the feeling of imminent death. Anxiety is not the same as fear, which is a response to a real or perceived immediate threat, whereas anxiety is the expectation of future threat. Anxiety is a feeling of uneasiness and worry, usually generalized and unfocused as an overreaction to a situation that is only subjectively seen as menacing. It is often accompanied by muscular tension, restlessness, fatigue and problems in concentration. Anxiety can be appropriate, but when experienced regularly the individual may suffer from an anxiety disorder.
People facing anxiety may withdraw from situations which have provoked anxiety in the past. There are various types of anxiety. Existential anxiety can occur when a person faces angst, an existential crisis, or nihilistic feelings. People can also face mathematical anxiety, somatic anxiety, stage fright, or test anxiety. Social anxiety and stranger anxiety are caused when people are apprehensive around strangers or other people in general. Furthermore, anxiety has been linked with physical symptoms such as IBS and can heighten other mental health illnesses such as OCD and panic disorder. The first step in the management of a person with anxiety symptoms is to evaluate the possible presence of an underlying medical cause, whose recognition is essential in order to decide its correct treatment. Anxiety symptoms may be masking an organic disease, or appear associated or as a result of a medical disorder.
Anxiety can be either a short term "state" or a long term "trait". Whereas trait anxiety represents worrying about future events, anxiety disorders are a group of mental disorders characterized by feelings of anxiety and fear. Anxiety disorders are partly genetic but may also be due to drug use, including alcohol, caffeine, and benzodiazepines (which are often prescribed to treat anxiety), as well as withdrawal from drugs of abuse. They often occur with other mental disorders, particularly bipolar disorder, eating disorders, major depressive disorder, or certain personality disorders. Common treatment options include lifestyle changes, medication, and therapy
The physiological symptoms of anxiety may include:
  • Neurological, as headache, paresthesias, vertigo, or presyncope.
  • Digestive, as abdominal pain, nausea, diarrhea, indigestion, dry mouth, or bolus.
  • Respiratory, as shortness of breath or sighing breathing.
  • Cardiac, as palpitations, tachycardia, or chest pain.
  • Muscular, as fatigue, tremors, or tetany.
  • Cutaneous, as perspiration, or itchy skin.
  • Uro-genital, as frequent urination, urinary urgency, dyspareunia, or impotence.

Animated
​THC, CBD, anxiety & paranoia 
Standard Medications 
Medication is typically prescribed for anxiety and depression treatment. Studies indicate that the SSRI’s and tricyclic antidepressants are very effective treatments for depression and anxiety. For extreme circumstances where the patient is experiencing panic and high levels of anxiety., benzodiazepines may also be prescribed for up to 3 weeks. This is typically how long it takes for most antidepressants to take effect. It is suggested that alongside medication, patients receive therapy to talk out their issues with a professional. but always do your research as these standard forms of medication have SOME side affects.
Medications for the Treatment of Anxiety and Depression
  • SSRI (selective serotonin reuptake inhibitor)
     ie) citalopram, escitalopram, fluoxetine, paroxetine, sertraline
  • SNRI (serotonin-norepinephrine reuptake inhibitor)
    ie) venlafaxine, duloxetine
  • Tricyclic antidepressant
    ie) amitriptyline, imipramine, nortriptyline
  • Benzodiazepine
    ie) alprazolam, clonazepam, diazepam, lorazepam
  • MAOI’s (monoamine oxidase inhibitors)
  • Anticonvulsants
  • Beta blockers
  • Antipsychotics
Typical side effects of anxiety and depression medication
  • Heart palpitations
  • Sweating
  • Tremor / Shakes
  • Insomnia
  • Sexual dysfunction
  • Weight gain
  • Nausea and vomiting
  • Headaches
  • High blood pressure
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How Cannabis Aids

Anandamide,         The Bliss Molecule: is the bodies version of a cannabiniod. The molecule in chocolate that give the                                                    blissful feeling, Also Naturally produced in the body; Anandamide is an important neurotransmitter,                                                  that’s also considered to be the “body’s own THC.” In fact, as it’s a source of joy and happiness,                                                        activating in many cases including during meditation. Cannabis can help correct this clinical deficiency.                                            (Anandamide consists of: Hydrogen, nitrogen, Oxygen,& Carbon.)
​Anandamide:                 is received by both CB1 & 2  cannabiniod receptors 
​Ananda, Sanskrit:         For Bliss
​PhytoCannabiniods:     are in some ways a simplified molecular version producing the same affects and more, keying into the                                             same receptors. Cannabiniods consist of: Hydrogen, Oxygen, & Carbon. (The 3 elements of life ( 1 Less                                           then Anandamide, Nitrogen ))

​In conclusion:                Cannabis over & above ALL the healing properties it possess helps Anxiety, stress, depression                                                           through the function of anandamide, introducing the bliss molecule Helps to alleviate the symptoms. 
Medical Cannabis Treatment of Anxiety
Anxiolytic
Serotonin is an essential neurotransmitter involved in the regulation of mood, sleep, appetite and libido. In the central nervous system serotonin communicates with numerous receptors responsible for a variety of biological functions.
The precise mechanism by which the endocannabinoid system modulates anxiety and 
depression is still being investagated, but CBD is postulated to act as an agonist to the 5HT1areceptor. Activation of the 5HT1a receptor is understood to modulate the release of serotonin in the brain. This hypothesis was confirmed in a study in which mice were pretreated with a 5HT1a antagonist, the antidepressant effects of CBD were absent. Further evidence of the role of 5HT1a is given by the observed similarities of CBD and isapirone (a 5HT1a partial agonist) in public speaking model.
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Neuroprotection
Impairment of the hippocampal neurogenesis has been associated with the pathogenesis of anxiety disorders and depression. CBD is though to stimulate hippocampal neurogenesis a property absent in CB1 knockout mice. The researchers postulate that the mechanism is hence CB1 dependent, CBD is thought to reduce the efficiency of FAAH hence reduce anandamide reuptake; hence the CB1 receptor is activated.

Homeostasis
​CBD & The Endocannabiniod System
​Cannabiniods, not just a nutrient.
Neurogenesis: Re-growing brain cells
In the mammalian brain, the CB1 receptor is one of the most abundant G protein–coupled receptors, accounting for most, if not all, of the centrally mediated effects of cannabinoids (5). both embryonic and adult hippocampal NS/PCs express CB1 receptors. The hippocampal dentate gyrus in the adult mammalian brain contains neural stem/progenitor cells (NS/PCs)
Brazilian Researchers Investigate CBD and how it may alleviate symptoms of Anxiety In Humans
Recruiting 10 patients with diagnosed Social Anxiety Disorder, the research team began by doing an analysis of patient brains via functional neuroimaging. Taking a look at the amount of bloodflow within various sections of the brain, the researchers were able to note how this changed upon CBD oil treatment.
In the first session, half of the patients received an oral dose of 400 mg of cannabidiol (CBD). The other half of the patients received placebos. Reversing these roles in the 2nd session., this gave all patients the opportunity of being treated with CBD. The results indicated CBD reduced anxiety in patients with social anxiety disorder and they pointed out how this was related to its effects on activity in limbic and paralimbic brain areas. According to the results of the study, cannabidiol (CBD) was associated with a significant decrease in subjective anxiety. Cerebral bloodflow after CBD treatment indicated an anxiolitic (anti-anxiety) effect in the areas of the brain that manage emotions.
Clinical Studies
1990 - Study ~ Cannabinoid Receptor Localization in Brain.
1997 - Study ~ Brain Chemicals Mimic Marijuana.
2000 - Study ~ The Cannabinoid System and Cytokine Network.
2009 - Study ~ Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress.
2009 - Editorial ~
The Endocannabinoid System in the Brain: From Biology to Therapy.
2009 - Study ~
Bidirectional regulation of novelty-induced behavioral inhibition by the endocannabinoid system.
Hampson et al., "Dual Effects of Anandamide on NMDA Receptor-Mediated Responses and Neurotransmission," Journal of Neurochemistry, Lippincott-Raven Publishers, 70(2):671-676 (1998).
2014, Study.  Vanderbilt University. Multiple Mechanistically Distinct Modes of Endocannabiniods Mobilization at                                            Central Amygdala glutamatergic Synapses.
2010 - Study ~  Motion Sickness, Stress and the Endocannabinoid System.
2005 - Study ~
Enhancing Cannabinoid Neurotransmission Augments the Extinction of Conditioned Fear.
Patents
​
US6630507  Cannabiniods as antioxidants & neuroprotectants

For More Clinical Studies Check Out,​
  • ​List of Cannabis Studies
  • ​List of Endocannabiniods & Cannabis Studies
  • List of THC & Cannabis Studies
  • List of CBD & Cannabis Studies
​For More Patents Check Out, 
  • ​Cannabis Patents
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  • Home
    • Cannabis/Hemp History >
      • Cannabis History Time line
    • Times Changing Global
    • Membership
    • Support the Cause
    • Contact Forum
  • Medical, Science & News
    • Cannabis daily News
    • Cannabis Science & Nutrition >
      • The Endocannabiniod System >
        • Cannabis Proteins, Amino Acids & Immunity
        • Cannabis: Female Reproduction, Fertility & Pregnacy >
          • Cannabis: Male Reproduction, Spermatogenesis & More
      • Cannabiniods/Cannabis Moleculer Structure & Composition >
        • THC, Overview; & How it works >
          • THCA, Overview
        • CBD: Dosage & How it Works >
          • CBD & Cannabinod Receptors, >
            • Single Molecule vs Whole Plant CBD
        • Anandamide, Overview: & How it works
        • Endocannabiniod: 2-AG, Overview
      • Terpenes Overview & Flavor Wheel >
        • Terpene: Beta-Caryophiliene >
          • Entorauge effect & Terpenes
        • Terpene, Alpha-Pinene
        • Terpene: Mycrene
        • Terpene: Humulene
      • List of Scientific Cannabis Studies >
        • List of Endocannabiniods & Cannabis Sudies >
          • List of ECS & Cannabis Anti-inflammation Studies >
            • Cannabis Patents
          • List of cannabis Studies & Huntington's Disease
          • E.C.S. & Cannabis Study Aversive memories (PTSD)
        • List of Delta 9-THC & Cannabis studies
        • List of CBD'S & Cannabis studies
    • Science of Extraction Methods & More >
      • Decarboxylation Temp. & Times Info.
      • fractional Distillation Protocol
      • Solvent Extraction"s & Comparison
      • Cold Press Extraction >
        • Cold press protocol preserving Carboxylic Form
    • Cannabis grow Info >
      • Growing Indoors >
        • Growing Cannabis in a Greenhouse >
          • Different Hydroponic Systems ; Growing, H20, O, EC, PH, Soils
          • Electric Conductivity & Cannabis
      • Growing Cannabis Outdoors
    • Tutorials
  • Cannabis/Hemp Innovation's
    • General Hemp Information >
      • Cannabis/Hemp Reversing Climate Change
      • Cannabis/Hemp Cleans Toxins & Radiation
    • 73 Cannabis / Hemp Product's A Tiny List >
      • Cannabis/Hemp Biofuel (Gas)
      • Hemp Batteries >
        • Plant & Electric terminology & conversion
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  • The Market
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    • publicly tradeed companies >
      • Stocks 101
    • LCBO Cannabis Page: Updates >
      • LCBO, Cannabis: Ontario Cities Selected for Store's >
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      • Alzheimer's
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      • (A) Anxiety
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      • (A) Apetite
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      • (A) Autoimmune Disease
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        • new disease page
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          • (O) Obesity/Weight Loss >
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            • (P) Postpartum Depression
            • (P) PTSD
          • (0) OCD
        • (N) Neurological Disorder
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        • (T) Tourettes Syndrome
      • (S) Stress
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  • Strain Index
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      • Ingrid
      • Northern Lights
      • Puprple Kush
    • Sativa Index >
      • Green Crack
      • Island Sweet Skunk
  • Industrial App's Index
    • new disease page